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Search Results for " oxidative stress "

ターゲット

BCL Caspase

159

阻害剤

130

天然化合物

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T25049	Allethrin		BCL , Caspase
	Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent.		BCL , Caspase
T7845	BTZO-1		Apoptosis
	BTZO-1 is an antioxidant response element (ARE) activator with cardioprotective activity.		Apoptosis
T7042	1,5-Isoquinolinediol		PARP
	1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol...		PARP
T8391	Cesium chloride	CsCl	Potassium Channel
	Cesium chloride (CsCl) is considered to be the most toxic of the alkali chlorides, inhibiting fungal growth.		Potassium Channel
T21902	ML351		Lipoxygenase
	ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).		Lipoxygenase
T5486	RU.521	RU320521	DNA , cGAS
	RU.521 (RU3205217) is a potent dsDNA inhibitor (IC50 : 700 nM), inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS.		DNA , cGAS
T5345	V-9302		Others
	V-9302 (V9302) is a competitive antagonist of transmembrane glutamine flux that selectively and potently targets the amino acid transporter ASCT2 (IC50: 9.6 uM).		Others
T6708	Tolcapone	Tasmar,Ro 40-7592	Apoptosis , Beta Amyloid , Transferase
	Tolcapone (Ro 40-7592) is a catechol-O-methyltransferase inhibitor used in the therapy of Parkinson disease as adjunctive therapy in combination with levodopa and carbidopa.		Apoptosis , Beta Amyloid , Transferase
T5827	BI-6C9		Apoptosis , Others , Mitochondrial Metabolism
	BI-6C9 is an inhibitor of tBid (Kd = 20 µM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.		Apoptosis , Others , Mitochondrial Metabolism
T23550	YM-750	YM 750	Acyltransferase
	YM-750 is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with an IC50 value of 0.18 μM. ACAT is an enzyme that catalyzes the conversion of cholesterol and long-chain fatty-acyl-coenzyme A into cholest...		Acyltransferase
TP1929L1	Saralasin acetate(34273-10-4 free base)		RAAS
	Saralasin acetate is a Non-selective angiotensin II antagonist.		RAAS
T5371	L-BUTHIONINE-(S,R)-SULFOXIMINE	L-Butionine sulfoximine	Others , Ferroptosis
	L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase (Ki <100 μM) that induces oxidative stress in cells by depleting GSH.		Others , Ferroptosis
T23146	PHA 568487 free base	PHA 568487	AChR
	The quinuclidine PHA 568487 free base is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated with the core scaffold and subsequently remove associated lia...		AChR
T6170	Elesclomol	STA-4783	Apoptosis , HSP , Reactive Oxygen Species
	Elesclomol (STA-4783) is an oxidative stress inducer and a highly lipophilic copper ion carrier. Elesclomol induces apoptosis in tumor cells and is used in copper death related studies. Elesclomol also inhibits FDX1-medi...		Apoptosis , HSP , Reactive Oxygen Species
T9516	Binodenoson	WRC 0470,MRE-0470,2-(cyclohexylmethylidenehydrazino)adenos	Adenosine Receptor
	Binodenoson (WRC 0470) is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stres...		Adenosine Receptor
T1487	Fluvastatin sodium	XU 62320 sodium,XU-62-320,Fluvastatin sodium salt	Ferroptosis , HMG-CoA Reductase , Autophagy
	Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol lowering agent.		Ferroptosis , HMG-CoA Reductase , Autophagy
T20684	2',7'-Dichlorofluorescein diacetate	Diacetyldichlorofluorescein,Leuco-dcf diacetate,Dcfh-DA,DCFDA	Others
	2',7'-Dichlorofluorescein diacetate (Diacetyldichlorofluorescein), a cell-permeable fluorogenic probe, is useful for the detection of nitric oxide (NO) and reactive oxygen species (ROS) and for the determination of the d...		Others
T1244	Celiprolol hydrochloride	Selecor,Selectrol	Adrenergic Receptor
	Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity. It is used in the management of ANGINA PECTORIS and HYPERTENSION.		Adrenergic Receptor
T14999	CORM-401		Others
	CORM-401 is an oxidant-sensitive CO-releasing molecule. It can be used in oxidative stress-mediated pathologies and the research of inflammatory.		Others
T10512	Prenyl-IN-1		Transferase
	Prenyl-IN-1 is a potent and selective prenylation inhibitor of geranylgeranyltransferase or farnesyltransferase.Prenyl-IN-1 shows anti-oxidative stress effects in a Parkinson's model. Prenyl-IN-1 showed anti-oxidative st...		Transferase
T18976	Dihydrofluorescein diacetate	Diacetyldihydrofluorescein	Others
	Dihydrofluorescein diacetate (Diacetyldihydrofluorescein) is a fluorescent probe for measuring oxidative stress in cell-free systems and cellular models.		Others
T21899	Misonidazole	SR-1354,SR1354,Ro 7-0582	GPX
	Misonidazole as a novel GPX inhibitors to cause oxidative stress in chemotherapy-resistant tumors.		GPX
T5913	Sulbutiamine	Bisibuthiamine	Antioxidant
	Sulbutiamine (Bisibuthiamine) is an antioxidant that act by inhibiting oxidative stress induced retinal ganglion cell death.		Antioxidant
T1710	Trolox		Apoptosis , Antioxidant , Ferroptosis , Reactive Oxygen Species
	Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.
T24905	TT01001	TT-01001,TT 01001,Ethyl 4-(3-(3,5-dichlorophenyl)thioureido)piperidine-1-carboxylate	Mitochondrial Metabolism
	TT01001 (Ethyl 4-(3-(3,5-dichlorophenyl)thioureido)piperidine-1-carboxylate) is a selective agonist of mitoNEET and reduces oxidative stress injury and neuronal apoptosis by improving mitochondrial dysfunction. TT01001 c...		Mitochondrial Metabolism
T72082	Compound T72082(SC)		ROS
	ROS-IN-1 is a mitochondrial ROS inhibitor that can be used to reduce oxidative stress or inhibit reactive oxygen species (ROS) production.		ROS
T65816	Prolyl-4-hydroxylase Inhibitor 11		Others
	Prolyl-4-hydroxylase Inhibitor 11, a novel proline 4-hydroxylase inhibitor, shows protective effects against oxidative stress and Cu(II) toxicity in Chlorella vulgaris.		Others
T16684	Puromycin aminonucleoside	NSC 3056	Apoptosis , Proteasome , Aminopeptidase , Antibacterial , Antibiotic
	Puromycin aminonucleoside (NSC-3056) increases podocyte permeability by modulating ZO-1 in an oxidative stress-dependent manner.
T24115	GSK854	GSK-854,GSK 854	Apoptosis
	GSK854 is a highly selective and potent inhibitor of troponin I interacting kinase (TNNI3K) that inhibits myocardial infarction-injured cellular pyroptosis and apoptosis in mice, which may limit oxidative stress, injury,...		Apoptosis
T14491	B022		NF-κB
	B022 is a selective and potent NF-κB-induced kinase (NIK) inhibitor (Ki: 4.2 nM), a chemical probe for the treatment of liver inflammation and injury.B022 protects the liver from inflammation and injury caused by oxidati...		NF-κB
TP1088	N-Acetylcarnosine	N-Acetyl-L-carnosine	Others
	N-Acetylcarnosine (N-Acetyl-L-carnosine) is thought to be able to combat some of the effects of oxidative stress as it has anti-oxidant properties.		Others
T15276	Ferroquine	SSR97193,Ferrochloroquine	Others
	Ferroquine (Ferrochloroquine) is a ferrocenyl analogue of Chloroquine with antimalarial activity. Ferroquine induces oxidative stress and the subsequent destruction of the membrane, resulting in parasiticidal effect on P...		Others
T34268	Raxofelast	IRFI016,IRFI-016,IRFI 016
	Raxofelast (IRFI-016) is a hydrophilic, non-systemic, vitamin-like antioxidant that reduces ischemia-reperfusion injury in testis. Raxofelast is a good candidate compound for stopping oxidative stress after acute testicu...
T8320	J14	J-14	Reactive Oxygen Species
	J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 μM). J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death		Reactive Oxygen Species
T22317	DRB18		transporter
	DRB18 is a highly effective pan-class inhibitor of glucose transporter proteins (GLUT). It significantly modulates energy-related metabolism in A549 cells by inducing alterations in the abundance of metabolites associate...		transporter
T8869	B355252		Others
	B355252 protects against cell death caused by glutamate-evoked oxidative stress. B355252 shows neuroprotective effect, potentiating nerve growth factor (NGF)-induced neurite outgrowth.		Others
T4360	ML385		Others , Ferroptosis , Nrf2
	ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity. ML385 has anti-inflammatory activity by modulating anti-oxidative stress through the inhibition of NRF2. ML385 also exhibits anti-tumor activity.		Others , Ferroptosis , Nrf2
T72072	2-benzylsulfanyl-6-methoxy-4-methylquinazoline		ROS
	2-benzylsulfanyl-6-methoxy-4-methylquinazoline can be used as a TRPML modulator for the treatment of diseases associated with TRPML activity, such as lysosomal storage disease, muscular dystrophy, oxidative stress or rea...		ROS
T27064	CP-312	CP312,Cardioprotectant 312	Reactive Oxygen Species , Autophagy
	CP-312 (Cardioprotectant 312) is an antioxidant defense response activator that protects hiPSC-CM viability by acting through induction of heme oxygenase-1 and targeting the antioxidant response network by inducing HMOX1...		Reactive Oxygen Species , Autophagy
T21405	Fluvastatin	Canef,XU-62320,Vastin,Cranoc,Lescol	HMG-CoA Reductase
	Fluvastatin (XU-62320) is a potent and competitive HMG-CoA reductase inhibitor (IC50: 8 nM) that inhibits oxidative stress in vascular smooth muscle cells through an Nrf2-dependent pathway, and is used for the reduction ...		HMG-CoA Reductase
T22963	McN-A 343		AChR
	McN-A 343 is a selective M1 muscarinic agonist known for its ability to stimulate muscarinic transmission in sympathetic ganglia. It has been found to effectively reduce inflammation and oxidative stress in experimental ...		AChR
T30087	Antroquinonol		Reactive Oxygen Species , Nrf2
	Antroquinonol is a ubiquinone derivative from Antrodia camphorata with anti-inflammatory and anticancer activities.Antroquinonol reduces oxidative stress and inhibits inflammation and sclerosis in mice with focal segment...		Reactive Oxygen Species , Nrf2
T77597	SXC 2023	(S)-2-acetamido-3-(4-methylbenzoylthio)propanoic acid	Others
	SXC 2023 ((S)-2-acetamido-3-(4-methylbenzoylthio)propanoic acid) is a therapeutic prodrug of N-acetyl-L-cysteine for the treatment of CNS disorders and neurocognitive disorders, and can be used to treat glutamatergic dys...		Others
T31615	Elsibucol	AGI-1096,UNII-O7T92N1Y8T,AGI 1096	Antioxidant
	Elsibucol (AGI 1096) is a VCAM1 inhibitor for the study of organ transplant rejection.Elsibucol is a metabolically stable propanol derivative with antioxidant, anti-inflammatory and anti-proliferative properties. It lowe...		Antioxidant
T33412	MitoPQ	MitoParaquat	Glucokinase , transporter
	MitoPQ (MitoParaquat) is a mitochondria-targeted small molecule compound that selectively enhances mitochondrial superoxide and hydrogen peroxide levels and inhibits insulin-stimulated glucose uptake and translocation of...		Glucokinase , transporter
T1319	Sodium diatrizoate	Diatrizoic acid sodium salt,Sodium amidotrizoate,Hypaque sodium,Diatrizoate sodium,amidotrizoate sodium,Triombrin	Apoptosis , Others
	Sodium diatrizoate (Hypaque sodium) is an iodinated radiopaque X-ray contrast medium. This contrast agent is used as a diagnostic aid in angiography, urography and radiography.It can induce mitochondrial renewal and oxid...		Apoptosis , Others
T72073	AKOS037652256
	AKOS037652256 can be used as a TRPML modulator for the treatment of diseases associated with TRPML activity such as lysosomal accumulation disorders, muscular dystrophy, common age-related neurodegenerative diseases, oxi...
T63750	α-Amylase-IN-1		Antioxidant , Amylase
	α-Amylase-IN-1 is an α-Amylase inhibitor (IC50: 0.5509 μM). α-Amylase-IN-1 has antioxidant activity with an IC50 value of 53.49 μM for scavenging of DPPH free radicals, and can be used in the study of diabetes and oxidat...		Antioxidant , Amylase
T16478	PF-04447943	PF 04447943,Edelinontrine,PF04447943	PDE
	PF-04447943 (Edelinontrine) is a potent and selective phosphodiesterase 9A inhibitor with an IC50 of 12 nM, which is 78-fold more selective than that used for other PDE family members (IC50>1000 nM).PF-04447943 exhibits ...		PDE
T6070	(E/Z)-Rigosertib sodium	(E/Z) ON-01910 sodium	PLK
	ON-01910 is a non-ATP-competitive PLK1 inhibitor(IC50 of 9 nM, in a cell-free assay). It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Rigosertib inhibits PI3K/Akt pathway and activates oxidativ...		PLK

Compounds

Target: Potassium Channel

Synonym: Tasmar,Ro 40-7592

Target: Apoptosis, Beta Amyloid, Transferase

BI-6C9

T5827

Synonym:

Target: Apoptosis, Others, Mitochondrial Metabolism

YM-750

T23550

Synonym: YM 750

Target: Acyltransferase

Saralasin acetate(34273-10-4 free base)

TP1929L1

Synonym:

Target: RAAS

L-BUTHIONINE-(S,R)-SULFOXIMINE

T5371

Synonym: L-Butionine sulfoximine

Target: Others, Ferroptosis

Target: Apoptosis, HSP, Reactive Oxygen Species

Binodenoson

T9516

Synonym: WRC 0470,MRE-0470,2-(cyclohexylmethylidenehydrazino)adenos

Target: Adenosine Receptor

Fluvastatin sodium

T1487

Synonym: XU 62320 sodium,XU-62-320,Fluvastatin sodium salt

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

2',7'-Dichlorofluorescein diacetate

T20684

Synonym: Diacetyldichlorofluorescein,Leuco-dcf diacetate,Dcfh-DA,DCFDA

Target: Others

Celiprolol hydrochloride

T1244

Synonym: Selecor,Selectrol

Target: Adrenergic Receptor

Dihydrofluorescein diacetate

T18976

Synonym: Diacetyldihydrofluorescein

Target: Others

Misonidazole

T21899

Synonym: SR-1354,SR1354,Ro 7-0582

Target: GPX

Sulbutiamine

T5913

Synonym: Bisibuthiamine

Target: Apoptosis, Antioxidant, Ferroptosis, Reactive Oxygen Species

TT01001

T24905

Synonym: TT-01001,TT 01001,Ethyl 4-(3-(3,5-dichlorophenyl)thioureido)piperidine-1-carboxylate

Target: Mitochondrial Metabolism

Prolyl-4-hydroxylase Inhibitor 11

T65816

Synonym:

Target: Others

Puromycin aminonucleoside

T16684

Synonym: NSC 3056

Target: Apoptosis, Proteasome, Aminopeptidase, Antibacterial, Antibiotic

GSK854

T24115

Synonym: GSK-854,GSK 854

Synonym: N-Acetyl-L-carnosine

Target: Others

Ferroquine

T15276

Synonym: SSR97193,Ferrochloroquine

Target: Others

Raxofelast

T34268

Synonym: IRFI016,IRFI-016,IRFI 016

Target: Reactive Oxygen Species

Target: Others, Ferroptosis, Nrf2

2-benzylsulfanyl-6-methoxy-4-methylquinazoline

Synonym: CP312,Cardioprotectant 312

Target: Reactive Oxygen Species, Autophagy

Fluvastatin

T21405

Synonym: Canef,XU-62320,Vastin,Cranoc,Lescol

Target: HMG-CoA Reductase

Target: Reactive Oxygen Species, Nrf2

SXC 2023

T77597

Synonym: (S)-2-acetamido-3-(4-methylbenzoylthio)propanoic acid

Target: Others

Elsibucol

T31615

Synonym: AGI-1096,UNII-O7T92N1Y8T,AGI 1096

Target: Antioxidant

MitoPQ

T33412

Synonym: MitoParaquat

Target: Glucokinase, transporter

Sodium diatrizoate

T1319

Synonym: Diatrizoic acid sodium salt,Sodium amidotrizoate,Hypaque sodium,Diatrizoate sodium,amidotrizoate sodium,Triombrin

Target: Apoptosis, Others

Target: Antioxidant, Amylase

PF-04447943

T16478

Synonym: PF 04447943,Edelinontrine,PF04447943

Target: PDE

(E/Z)-Rigosertib sodium

T6070

Synonym: (E/Z) ON-01910 sodium

Target: PLK

カタログ番号	製品名	別名	ターゲット
T2738	Dehydroandrographolide		NOS , Influenza Virus
	Dehydroandrographolide is a natural compound extracted from herbal medicine Andrographis paniculata (Burm f) Nees.		NOS , Influenza Virus
TC0039	Vasicinone		Others
	Vasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease.(S)-Vasicinone exhibits antiprolifer...		Others
T7982	3,6-Dihydroxyflavone		Others
	3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.		Others
T5783	Rosamultin		Antioxidant , HIV Protease
	Rosamultin has antioxidant, antiinflammatory/antinociceptive properties,and has anti-human immunodeficiency virus (HIV) activity.		Antioxidant , HIV Protease
T8678	Naphthazarin	5,8-Dihydroxy-1,4-naphthoquinone,DHNQ	Apoptosis
	Naphthazarin (5,8-Dihydroxy-1,4-naphthoquinone) is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, inter...		Apoptosis
T41358	2-Hydroxybenzylamine		Others
	2-Hydroxybenzylamine, a potent small molecule scavenger of IsoLGs, sequesters the reactive species as inert adducts. 2-Hydroxybenzylamine may be used to decrease early recurrence of atrial fibrillation and other atrial a...		Others
T3394	Timosaponin BII	Prototimosaponin A III	Beta Amyloid , Others , BACE
	Timosaponin BII (Prototimosaponin A III) has anti-dementia activity and may be useful for the treatment of type 2 diabetes. Timosaponin BII has antioxidant activity, can inhibit the up-regulation of BACE1 and reduced the...		Beta Amyloid , Others , BACE
TN2244	Sulfuretin		NF-κB , Autophagy
	Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 thr...		NF-κB , Autophagy
TN1926	Methyl caffeate	Methyl caffeate acid	Others , Antibacterial
	Methyl caffeate (Methyl caffeate acid) acid		Others , Antibacterial
T2800	L-Theanine		Apoptosis , Others
	L-Theanine is a relaxing and nondietary amino acid found pretty much exclusively in teas from Camellia sinensis and is known to promote relaxation without sedation.		Apoptosis , Others
T10148	4-Hydroxynonenal	4-HNE	Dehydrogenase , Endogenous Metabolite
	4-Hydroxynonenal (4-HNE) (4-HNE) is an oxidative/nitrosative stress biomarker. It is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2).		Dehydrogenase , Endogenous Metabolite
TJO2742	DL-Methionine	methionine,Acimetion,Racemethionine	Parasite
	DL-Methionine (Acimetion) is an amino acid. Amino acids are the building blocks that our bodies use to make proteins. DL-Methionine is found in meat, fish, and dairy products. It plays an important role in the many funct...		Parasite
T2230	Paeoniflorin	Peoniflorin	HSP , COX
	Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.		HSP , COX
T0626	Uric Acid	2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate	Reactive Oxygen Species , Endogenous Metabolite , Phosphorylase
	Uric Acid (Lithic acid) is an oxidation product of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE ...
TN6339	(R)-5-Hydroxy-1,7-diphenylheptan-3-one	(5R)-Dihydroyashabushiketol	Others
	(R)-5-Hydroxy-1,7-diphenylheptan-3-one ((5R)-Dihydroyashabushiketol) is extracted from the rhizomes of Alpinia officinarum, a Chinese medicinal herb. (R)-5-Hydroxy-1,7-diphenylheptan-3-one inhibits melanogenesis in theop...		Others
T2198	Arecoline hydrobromide	Arecoline HBr,Arecoline bromide	AChR
	Arecoline hydrobromide (Arecoline HBr) is a muscarinic acetylcholine receptor agonist.		AChR
T3S1068	Oxyresveratrol	trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,Tetrahydroxystilbene	Tyrosinase , Autophagy , HSV
	1. Oxyresveratro can inhibit tyrosinase activity. 2. Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive gliosis. 3. Oxyresveratrol (trans-Oxyresveratrol) has antioxid...		Tyrosinase , Autophagy , HSV
T3982	Vulpinic Acid	Vulpic acid,Pulvinic acid methyl ester	Others
	Vulpinic Acid (Pulvinic acid methyl ester) is a lichen metabolite with anti-inflammatory, antibacteria, properties, plant growth inhibitor.		Others
T6S0117	Avicularin	Fenicularin	ERK
	Avicularin (Fenicularin) has anti-allergic, anti-inflammatory, hepatoprotective, antioxidant, anti-tumor and other activities. It ameliorates human hepatocellular carcinoma by modulating the activities of NF-κB(p65), COX...		ERK
T8193	α-Thujone	Thujone,ALPHA-(-)-THUJONE	Apoptosis , Reactive Oxygen Species , GABA Receptor , AChR , Parasite , Autophagy
	α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
T2870	Matrine	Vegard,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine	Mitophagy , Ferroptosis , Opioid Receptor , Autophagy
	Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.		Mitophagy , Ferroptosis , Opioid Receptor , Autophagy
T37710	5-Hydroxyoxindole		Reactive Oxygen Species
	5-Hydroxyoxindole has been identified as a urinary metabolite of indole, which is produced from tryptophane via the tryptophanase activity of gut bacteria [1]. 5-Hydroxyoxindole has lipid peroxidation inhibition activit...		Reactive Oxygen Species
T20597	Alginic acid	Protanal LF,Snow acid algin G,Kelacid,Sazzio,Norgine	Apoptosis , Autophagy , Histamine Receptor
	Alginic acid (Snow acid algin G) is a natural polysaccharide extracted from brown seaweeds with anti-anaphylactic and anti-inflammatory activities. Alginic acid inhibits histamine release and can be used in the food indu...		Apoptosis , Autophagy , Histamine Receptor
T8704	4-hydroxyphenyl acetate		Nrf2
	4-Acetoxyphenol Prevents RPE Oxidative Stress-Induced Necrosis by Functioning as an NRF2 Stabilizer		Nrf2
T6S1768	Narcissin	Isorhamnetin 3-Rutinoside,Narcissoside	Antioxidant
	Narcissin (Isorhamnetin 3-Rutinoside), with synergism of B.flavum flavonoid and rutin, could be responsible for stronger protection against mitochondrial induced oxidative stress.		Antioxidant
T2805	Chlorogenic Acid	NSC-407296,3-O-Caffeoylquinic acid,Heriguard	Others , Influenza Virus , Reactive Oxygen Species , HIF/HIF Prolyl-Hydroxylase , Endogenous Metabolite , Antibacterial
	Chlorogenic Acid (NSC-407296) is a naturally occurring phenolic acid which is a carcinogenic inhibitor. It has also been shown to prevent paraquat-induced oxidative stress in rats.
T6S1966	Curculigoside	Curculigoside A	Antioxidant , NF-κB , JAK , STAT
	1. Curculigoside (Curculigoside A) can prevent bone loss , improve osteogenesis and inhibit osteoclastogenesis of hAFSCs, suggesting its potential use to regulate hAFSC osteogenic differentiation for treating bone disord...		Antioxidant , NF-κB , JAK , STAT
TN1461	(-)-Butin	Butin	Akt , PI3K , Nrf2
	(-)-Butin (Butin) has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction; it attenuates oxidative stress by activating Nrf2-mediated Mn SO...		Akt , PI3K , Nrf2
T0335	Sodium salicylate	Salicylic acid sodium salt,2-Hydroxybenzoic acid sodium salt	Apoptosis , NF-κB , COX , S6 Kinase , Autophagy
	Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.		Apoptosis , NF-κB , COX , S6 Kinase , Autophagy
TN1600	Eclalbasaponin I		Others
	Eclalbasaponin I has anti-oxidative, and antitumor activities, it reduces oxidative stress-induced neural cell death by autophagy activation, it can dose-dependently inhibit the proliferation of hepatoma cell smmc-7721 w...		Others
T3405	[6]-Gingerol	6-Gingerol,gingerol,(S)-(+)-[6]Gingerol	Apoptosis , AMPK
	[6]-Gingerol ((S)-(+)-[6]Gingerol), an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for Yous tumors in the pancreas, ovaries, breast tissue, the bowel, among other tissues.		Apoptosis , AMPK
TN1067	Galloylpaeoniflorin	6'-O-Galloyl paeoniflorin	NF-κB , Androgen Receptor , ROS
	Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress. Galloylpaeoniflorin is also an inhibtior of NF-κB and DNA cleavage.		NF-κB , Androgen Receptor , ROS
T5665	Geraniol		Others , Endogenous Metabolite , Antifungal
	geraniol provides a potent protective effect against cardiac dysfunction induced by diabetes. This ameliorative effect could be attributed to its suppression of oxidative stress.		Others , Endogenous Metabolite , Antifungal
T4868	Gamma-Linolenic acid	gamolenic acid,γ-Linolenic acid	Endogenous Metabolite
	gamma-Linolenic acid (gamolenic acid), is an unsaturated fatty acid synthesized from linoleic acid (LA) by the enzyme delta-6-desaturase. Research on hepatocellular cell lines has shown γ-Linolenic Acid to have induced r...		Endogenous Metabolite
T19418	Methionine sulfoxide		Endogenous Metabolite
	Methionine sulfoxide, an oxidation product of methionine formed through interaction with reactive oxygen species, serves as a biomarker for oxidative stress in vivo.		Endogenous Metabolite
TN1058	Pelargonidin chloride		NOS , Reactive Oxygen Species , Nrf2 , NO Synthase
	Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels through Keap1/Nrf2 signaling pathway.		NOS , Reactive Oxygen Species , Nrf2 , NO Synthase
T0632	3,4,5-Trimethoxybenzoic acid	Gallic acid trimethyl ether,Eudesmic acid,Trimethylgallic Acid,Benzoic acid,Tri-O-methylgallic acid	Antioxidant
	3,4,5-Trimethoxybenzoic acid (Gallic acid trimethyl ether) are potent antioxidants and inhibitor of cytokine production. It can ameliorate chronic stress-induced various behavioral and biochemical alterations in mice. It...		Antioxidant
TN6778	Umbelliprenin	7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-oneUmbelliprenin	IL Receptor
	Umbelliprenin (7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-oneUmbelliprenin) alleviated neuropathic pain, and decreased serum IL-6 levels and oxidative stress.		IL Receptor
T8255	(±)-Catechin	(±)-Catechin hydrate	ROS , COX
	(±)-Catechin ((±)-Catechin hydrate) hydrate is a natural product,has antioxidant activity and is effective in reducing oxidative stress.		ROS , COX
T3671	Vitexin-2"-O-rhamnoside	2''-O-Rhamnosylvitexin,Vitexin-2-O-rhaMnoside,Vitexin-2''-O-rhamnoside,Apigenin-8-C-glucoside	Others
	Vitexin-2"-O-rhamnoside (Apigenin-8-C-glucoside) is a compound contributes to the protection against H O -mediated oxidative stress damage.		Others
T25253	Cinnamtannin B-1	Cinnamtannin B1 (constituent of cinnamomum verum bark),LDN 0022358,LDN-0022358,LDN0022358	Antioxidant , COX
	Cinnamtannin B-1 (LDN 0022358) is an A-type proanthocyanidin contained in several plant species such as Vaccinium vitis-idaea, Laurus nobilis L., Cinnamomum zeylanicum, and Lindera umbellata. It is a potent antioxidant a...		Antioxidant , COX
T6S1538	Neochlorogenic acid	trans-5-O-Caffeoylquinic acid,Neochlorogenate,5-O-Caffeoylquinic acid	TNF , NF-κB , COX , Antibacterial , Interleukin
	Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.		TNF , NF-κB , COX , Antibacterial , Interleukin
T3774	Gracillin		cell cycle arrest
	Gracillin can induce cell cycle arrest, oxidative stress, and apoptosis in HL60 cells, and has the potential to be developed as an antitumor agent. Gracillin can be selected as lead compounds for the development of new d...		cell cycle arrest
T6S1294	Nicotiflorin	Nictoflorin,Kaempferol-3-O-Rutinoside,Nicotifloroside	Others
	1. Nicotiflorin (Kaempferol-3-O-Rutinoside) has potential therapeutic effects on cerebral ischemic illness. 2. Nicotiflorin has protective effects on reducing memory dysfunction, energy metabolism failure and oxidative s...		Others
T2S1008	Oxysophoridine	Sophoridine N-oxide	Apoptosis , Antioxidant
	Oxysophoridine (Sophoridine N-oxide) has a protective effect on focal cerebral ischemic injury through antioxidant and anti-apoptotic mechanisms; it may be a potential neuroprotective agent for cerebral ischemia injury, ...		Apoptosis , Antioxidant
T6S0721	Orientin	Lutexin,Luteolin-8-glucoside	Others
	1. Orientin (Luteolin-8-glucoside) may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vascular barrier int...		Others
T19397	L-Methionine sulfoxide	H-Met(O)-OH	Endogenous Metabolite
	L-Methionine sulfoxide (H-Met(O)-OH) (H-Met(O)-OH) is a metabolite of Methionine. (H-Met(O)-OH) modulates oxidative stress and purinergic signaling parameters, and induces M1/classical macrophage polarization.		Endogenous Metabolite
T5968	DL-Homocysteine thiolactone hydrochloride	DL-Homocysteinethiolactone hydrochloride	Endogenous Metabolite
	DL-Homocysteine thiolactone hydrochloride (DL-Homocysteinethiolactone hydrochloride) is a cysteine derivative that binds to and induces conformational changes in various plasma proteins, slowing coagulation and inducing ...		Endogenous Metabolite
T3S0137	Bavachalcone		Antibacterial , Antibiotic
	Bavachalcone is a major bioactive compounds isolated from Psoralea corylifolia L. it may be useful as a therapeutic drug for bone resorption-associated diseases.Bavachalcone can protect the endothelial function by increa...		Antibacterial , Antibiotic
T3834	8-Epideoxyloganic acid		ROS , Immunology/Inflammation related
	8-Epideoxyloganic acid possesses bioactivities of analgesia, homeostasis and anti-inflammatory. It has the potential to serve as anti-inflammatory agents during oxidative stress, the inhibition of ROS production, possibl...		ROS , Immunology/Inflammation related
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天然物製品

Dehydroandrographolide

T2738

Synonym:

Target: NOS, Influenza Virus

Target: Antioxidant, HIV Protease

Naphthazarin

T8678

Synonym: 5,8-Dihydroxy-1,4-naphthoquinone,DHNQ

Synonym: Prototimosaponin A III

Target: Beta Amyloid, Others, BACE

Sulfuretin

TN2244

Synonym:

Target: NF-κB, Autophagy

Methyl caffeate

TN1926

Synonym: Methyl caffeate acid

Target: Others, Antibacterial

L-Theanine

T2800

Synonym:

Target: Apoptosis, Others

4-Hydroxynonenal

T10148

Synonym: 4-HNE

Target: Dehydrogenase, Endogenous Metabolite

DL-Methionine

TJO2742

Synonym: methionine,Acimetion,Racemethionine

Synonym: 2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate

Target: Reactive Oxygen Species, Endogenous Metabolite, Phosphorylase

(R)-5-Hydroxy-1,7-diphenylheptan-3-one

TN6339

Synonym: (5R)-Dihydroyashabushiketol

Target: Others

Arecoline hydrobromide

T2198

Synonym: Arecoline HBr,Arecoline bromide

Target: AChR

Oxyresveratrol

T3S1068

Synonym: trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,Tetrahydroxystilbene

Target: Tyrosinase, Autophagy, HSV

Vulpinic Acid

T3982

Synonym: Vulpic acid,Pulvinic acid methyl ester

Synonym: Thujone,ALPHA-(-)-THUJONE

Target: Apoptosis, Reactive Oxygen Species, GABA Receptor, AChR, Parasite, Autophagy

Matrine

T2870

Synonym: Vegard,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine

Target: Mitophagy, Ferroptosis, Opioid Receptor, Autophagy

5-Hydroxyoxindole

T37710

Synonym:

Target: Reactive Oxygen Species

Alginic acid

T20597

Synonym: Protanal LF,Snow acid algin G,Kelacid,Sazzio,Norgine

Target: Apoptosis, Autophagy, Histamine Receptor

4-hydroxyphenyl acetate

Synonym: Isorhamnetin 3-Rutinoside,Narcissoside

Target: Antioxidant

Chlorogenic Acid

T2805

Synonym: NSC-407296,3-O-Caffeoylquinic acid,Heriguard

Target: Others, Influenza Virus, Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, Endogenous Metabolite, Antibacterial

Curculigoside

T6S1966

Synonym: Curculigoside A

Target: Antioxidant, NF-κB, JAK, STAT

(-)-Butin

TN1461

Synonym: Butin

Target: Akt, PI3K, Nrf2

Sodium salicylate

T0335

Synonym: Salicylic acid sodium salt,2-Hydroxybenzoic acid sodium salt

Target: Apoptosis, NF-κB, COX, S6 Kinase, Autophagy

Synonym: 6-Gingerol,gingerol,(S)-(+)-[6]Gingerol

Target: Apoptosis, AMPK

Galloylpaeoniflorin

TN1067

Synonym: 6'-O-Galloyl paeoniflorin

Target: NF-κB, Androgen Receptor, ROS

Geraniol

T5665

Synonym:

Target: Others, Endogenous Metabolite, Antifungal

gamma-Linolenic acid

T4868

Synonym: gamolenic acid,γ-Linolenic acid

Target: Endogenous Metabolite

Methionine sulfoxide

T19418

Synonym:

Target: Endogenous Metabolite

Pelargonidin chloride

TN1058

Synonym:

Target: NOS, Reactive Oxygen Species, Nrf2, NO Synthase

3,4,5-Trimethoxybenzoic acid

T0632

Synonym: Gallic acid trimethyl ether,Eudesmic acid,Trimethylgallic Acid,Benzoic acid,Tri-O-methylgallic acid

Target: Antioxidant

Umbelliprenin

TN6778

Synonym: 7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-oneUmbelliprenin

Target: IL Receptor

(±)-Catechin

T8255

Synonym: (±)-Catechin hydrate

Target: ROS, COX

Vitexin-2"-O-rhamnoside

T3671

Synonym: 2''-O-Rhamnosylvitexin,Vitexin-2-O-rhaMnoside,Vitexin-2''-O-rhamnoside,Apigenin-8-C-glucoside

Target: Others

Cinnamtannin B-1

T25253

Synonym: Cinnamtannin B1 (constituent of cinnamomum verum bark),LDN 0022358,LDN-0022358,LDN0022358

Target: Antioxidant, COX

Neochlorogenic acid

T6S1538

Synonym: trans-5-O-Caffeoylquinic acid,Neochlorogenate,5-O-Caffeoylquinic acid

Target: TNF, NF-κB, COX, Antibacterial, Interleukin

Gracillin

T3774

Synonym:

Target: cell cycle arrest

Nicotiflorin

T6S1294

Synonym: Nictoflorin,Kaempferol-3-O-Rutinoside,Nicotifloroside

Target: Others

Oxysophoridine

T2S1008

Synonym: Sophoridine N-oxide

Target: Apoptosis, Antioxidant

Orientin

T6S0721

Synonym: Lutexin,Luteolin-8-glucoside

Target: Others

L-Methionine sulfoxide

T19397

Synonym: H-Met(O)-OH

Target: Endogenous Metabolite

DL-Homocysteine thiolactone hydrochloride

T5968

Synonym: DL-Homocysteinethiolactone hydrochloride

Target: Endogenous Metabolite

Bavachalcone

T3S0137

Synonym:

Target: Antibacterial, Antibiotic

8-Epideoxyloganic acid

T3834

Synonym:

Target: ROS, Immunology/Inflammation related

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04460	OXSR1 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	Oxidative stress-responsive 1 protein (OXSR1), also known as Serine/threonine-protein kinase OSR1, is a member of the Ser/Thr protein kinase family of proteins. OXSR1 regulates downstream kinases in response to environme...
TMPY-00541	LON PROTEASE Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Lon protease, an ATP-dependent mitochondrial protease, is important in mitochondrial protein maintenance. Lon protease is a multifunctional enzyme, and its functions include the degradation of damaged proteins and natura...
TMPY-01403	VNN1 Protein, Human, Recombinant (His)	Human	HEK293
	Pantetheinase, also known as Pantetheine hydrolase, Vascular non-inflammatory molecule 1, Vanin-1, and VNN1, is a cell membrane protein which belongs to the CN hydrolase family and BTD/VNN subfamily. Vanin-1 contains one...
TMPH-02681	GPX7 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks.
TMPH-00641	YTFE Protein, E. coli, Recombinant (GST)	E. coli	E. coli
	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
TMPH-03443	GPX2 Protein, S. cerevisiae, Recombinant (His & Myc)	Saccharomyces cerevisiae	E. coli
	Glutathione peroxidase-like protein that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress. Plays an important role in the oxidative stress-induced response in the pres...
TMPH-03275	Cytoglobin Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Plays a role in the development of liver fibrosis. Has a peroxidase activity.
TMPY-02043	PARK7/DJ-1 Protein, Human, Recombinant (His)	Human	E. coli
	Parkinson's disease locus DJ-1 (PARK7) is a differentially expressed transcript. DJ-1 plays a physiologic role in protection of erythroid cells from oxidant damage, a function unmasked in the context of oxidative stress....
TMPH-01397	LANCL1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Functions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during norma...
TMPY-02299	ALDH3A1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Aldehyde dehydrogenase 3A1 (ALDH3A1) is a metabolic enzyme that catalyzes the oxidation of various aldehydes. Certain types of epithelial tissues in mammals, especially those continually exposed to environmental stress (...
TMPH-00093	GAPC1, cytosolic Protein, Arabidopsis thaliana, Recombinant (His & Myc)	Arabidopsis thaliana	E. coli
	Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Essential for the maintenance of cellular ATP levels and carboh...
TMPH-03054	Asp f3 Protein, Neosartorya fumigata, Recombinant (His & SUMO)	Neosartorya fumigata	E. coli
	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxide...
TMPH-03721	IbpA Protein, Yersinia pestis bv. Antiqua, Recombinant (His)	Yersinia pestis	E. coli
	Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the Ibp...
TMPH-00072	2-Cys Prx A Protein, Arabidopsis thaliana, Recombinant (His)	Arabidopsis thaliana	Yeast
	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxide...
TMPH-02199	TXNRD2 Protein, Human, Recombinant (His)	Human	E. coli
	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxide...
TMPH-02153	Sulfiredoxin-1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduct...
TMPJ-01248	Cytoglobin/CYGB Protein, Human, Recombinant (His)	Human	E. coli
	Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be...
TMPJ-00720	TXNDC12 Protein, Human, Recombinant (His)	Human	Human Cells
	Thioredoxin Domain-Containing Protein 12 belongs to the thioredoxin superfamily. In this family, proteins possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defens...
TMPJ-01076	FKBP4 Protein, Human, Recombinant (His)	Human	E. coli
	FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone recepto...
TMPH-00794	Dps Protein, Helicobacter pylori, Recombinant (His & SUMO)	Helicobacter pylori	E. coli
	Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical produ...
TMPH-02469	PDK1 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus
	Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, a...
TMPH-02661	Frataxin/FXN Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress thr...
TMPY-02544	FANCA Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	FANCA is one of the six known Fanconi anemia gene products (FANCA, FANCC, FANCD2, FANCE, FANCF, and FANCG proteins). Fanconi anemia (FA) is a genetic disorder predisposing to aplastic anemia and cancer characterized by h...
TMPJ-00379	AOC3 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Membrane primary amine oxidase(AOC3), also known as vascular adhesion protein (VAP-1) and HPAO, this protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family. VAP-1 is a type 1 membrane-bound glycop...
TMPH-01761	Neuroglobin Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhi...
TMPY-02201	Peroxiredoxin 6 Protein, Human, Recombinant (His)	Human	E. coli
	PRDX6, a member of antioxidant protein superfamily, plays an important role in oxidative stress, catabolism of lipids and phospholipid lipisomes. Peroxiredoxin 6 (PRDX6) is involved in redox regulation of the cell and is...
TMPY-01588	ALDH7A1 Protein, Human, Recombinant (His)	Human	E. coli
	ALDH7A1 (Aldehyde dehydrogenase 7 family, member A1) is a member of subfamily 7 in the aldehyde dehydrogenase family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol...
TMPH-01502	Humanin Protein, Human, Recombinant (GST)	Human	E. coli
	Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective e...
TMPJ-00105	SOD2 Protein, Human, Recombinant (His)	Human	Human Cells
	Superoxide Dismutase (SOD2) belongs to the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic super...
TMPY-03823	H Cadherin Protein, Rat, Recombinant (hFc)	Rat	HEK293
	CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from ...
TMPY-03948	H Cadherin Protein, Rat, Recombinant	Rat	HEK293
	CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from ...
TMPY-00450	H Cadherin Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from ...
TMPK-01168	LOX-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	LOX-1 is a transmembrane glycoprotein that binds to and internalizes ox-LDL.LOX-1 gene deletion in mice and anti-LOX-1 therapy has been shown to decrease inflammation, oxidative stress and atherosclerosis. LOX-1 deletion...
TMPY-00601	H Cadherin Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from ...
TMPY-03798	H Cadherin Protein, Rat, Recombinant (His)	Rat	HEK293
	CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from ...
TMPY-04260	P38 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	MAPK14 contains 1 protein kinase domain and belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as prol...
TMPH-02660	Frataxin/FXN Protein, Mouse, Recombinant (His)	Mouse	Yeast
	Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress thr...
TMPH-03295	Frataxin/FXN Protein, Rat, Recombinant	Rat	E. coli
	Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress thr...
TMPK-00693	HSP27/HSPB1 Protein, Human, Recombinant (His)	Human	E. coli
	Heat shock protein beta-1 (HSPB1, also known as HSP27) is a small heat shock protein involved in many cellular processes and reportedly protects cells against oxidative stress. This protein is expressed only in insulin-d...
TMPH-02428	Frataxin Protein, Cynomolgus, Recombinant (His)	Cynomolgus	E. coli
	Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress thr...
TMPH-01503	Humanin Protein, Human, Recombinant (hFc)	Human	HEK293
	Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective e...
TMPY-02072	HSF1 Protein, Human, Recombinant (His)	Human	E. coli
	Heat shock factor protein 1, also known as heat shock transcription factor 1, HSF1, and HSTF1, is a cytoplasm and nucleus protein that belongs to the HSF family. HSF1 is the major transcription factor of HSPs (heat shock...
TMPJ-00380	AOC3 Protein, Human, Recombinant (His)	Human	Human Cells
	Vascular adhesion protein-1(VAP-1) is a copper amine oxidase with a topaquinone cofactor.VAP-1 is a type II integral membrane protein, but a soluble form of the enzyme is present in human serum, and its level increases i...
TMPH-03571	WalK Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Member of the two-component regulatory system WalK/WalR that regulates genes involved in cell wall metabolism, virulence regulation, biofilm production, oxidative stress resistance and antibiotic resistance via direct or...
TMPH-03274	ATF-4 Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	Transcription factor that binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') and displays two biological functions, as regulator of metabolic and redox processes under normal cellular conditions, an...
TMPH-02929	TXNIP Protein, Mouse, Recombinant (His)	Mouse	Yeast
	May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated ...
TMPH-02200	TXNIP Protein, Human, Recombinant (B2M & His)	Human	in vitro E. coli expression system
	May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated ...
TMPY-04406	Protein Kinase D2/PRKD2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Serine/threonine-protein kinase D2, also known as PRKD2 and PKD2, is a cytoplasm and membrane protein that belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and PKD subfamily. PRKD2 / PKD2 is ...
TMPH-01356	Frataxin/FXN Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress thr...
TMPH-01056	Caspase-3 Protein, Human, Recombinant (His)	Human	E. coli
	Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activ...
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OXSR1 Protein, Human, Recombinant (GST)

TMPY-04460

Species: Human

Expression System: Baculovirus-Insect Cells

LON PROTEASE Protein, E. coli, Recombinant (His)

TMPY-00541

Species: E. coli

Expression System: E. coli

VNN1 Protein, Human, Recombinant (His)

TMPY-01403

Species: Human

Expression System: HEK293

GPX7 Protein, Mouse, Recombinant (His & Myc)

TMPH-02681

Species: Mouse

Expression System: E. coli

YTFE Protein, E. coli, Recombinant (GST)

TMPH-00641

Species: E. coli

Expression System: E. coli

GPX2 Protein, S. cerevisiae, Recombinant (His & Myc)

TMPH-03443

Species: Saccharomyces cerevisiae

Expression System: E. coli

Cytoglobin Protein, Rat, Recombinant (His & Myc)

TMPH-03275

Species: Rat

Expression System: E. coli

PARK7/DJ-1 Protein, Human, Recombinant (His)

TMPY-02043

Species: Human

Expression System: E. coli

LANCL1 Protein, Human, Recombinant (His & Myc)

TMPH-01397

Species: Human

Expression System: E. coli

ALDH3A1 Protein, Human, Recombinant (His)

TMPY-02299

Species: Human

Expression System: Baculovirus-Insect Cells

GAPC1, cytosolic Protein, Arabidopsis thaliana, Recombinant (His & Myc)

TMPH-00093

Species: Arabidopsis thaliana

Expression System: E. coli

Asp f3 Protein, Neosartorya fumigata, Recombinant (His & SUMO)

TMPH-03054

Species: Neosartorya fumigata

Expression System: E. coli

IbpA Protein, Yersinia pestis bv. Antiqua, Recombinant (His)

TMPH-03721

Species: Yersinia pestis

Expression System: E. coli

2-Cys Prx A Protein, Arabidopsis thaliana, Recombinant (His)

TMPH-00072

Species: Arabidopsis thaliana

Expression System: Yeast

TXNRD2 Protein, Human, Recombinant (His)

TMPH-02199

Species: Human

Expression System: E. coli

Sulfiredoxin-1 Protein, Human, Recombinant (His & Myc)

TMPH-02153

Species: Human

Expression System: E. coli

Cytoglobin/CYGB Protein, Human, Recombinant (His)

TMPJ-01248

Species: Human

Expression System: E. coli

TXNDC12 Protein, Human, Recombinant (His)

TMPJ-00720

Species: Human

Expression System: Human Cells

FKBP4 Protein, Human, Recombinant (His)

TMPJ-01076

Species: Human

Expression System: E. coli

Dps Protein, Helicobacter pylori, Recombinant (His & SUMO)

TMPH-00794

Species: Helicobacter pylori

Expression System: E. coli

PDK1 Protein, Mouse, Recombinant (His)

TMPH-02469

Species: Mouse

Expression System: Baculovirus

Frataxin/FXN Protein, Mouse, Recombinant (E. coli, His)

TMPH-02661

Species: Mouse

Expression System: E. coli

FANCA Protein, Human, Recombinant (His)

TMPY-02544

Species: Human

Expression System: Baculovirus-Insect Cells

AOC3 Protein, Human, Recombinant (hFc)

TMPJ-00379

Species: Human

Expression System: Human Cells

Neuroglobin Protein, Human, Recombinant (His & SUMO)

TMPH-01761

Species: Human

Expression System: E. coli

Peroxiredoxin 6 Protein, Human, Recombinant (His)

TMPY-02201

Species: Human

Expression System: E. coli

ALDH7A1 Protein, Human, Recombinant (His)

TMPY-01588

Species: Human

Expression System: E. coli

Humanin Protein, Human, Recombinant (GST)

TMPH-01502

Species: Human

Expression System: E. coli

SOD2 Protein, Human, Recombinant (His)

TMPJ-00105

Species: Human

Expression System: Human Cells

H Cadherin Protein, Rat, Recombinant (hFc)

TMPY-03823

Species: Rat

Expression System: HEK293

H Cadherin Protein, Rat, Recombinant

TMPY-03948

Species: Rat

Expression System: HEK293

H Cadherin Protein, Mouse, Recombinant (His)

TMPY-00450

Species: Mouse

Expression System: HEK293

LOX-1 Protein, Mouse, Recombinant (His)

TMPK-01168

Species: Mouse

Expression System: HEK293

H Cadherin Protein, Mouse, Recombinant (hFc)

TMPY-00601

Species: Mouse

Expression System: HEK293

H Cadherin Protein, Rat, Recombinant (His)

TMPY-03798

Species: Rat

Expression System: HEK293

p38 Protein, Human, Recombinant (His)

TMPY-04260

Species: Human

Expression System: Baculovirus-Insect Cells

Frataxin/FXN Protein, Mouse, Recombinant (His)

TMPH-02660

Species: Mouse

Expression System: Yeast

Frataxin/FXN Protein, Rat, Recombinant

TMPH-03295

Species: Rat

Expression System: E. coli

HSP27/HSPB1 Protein, Human, Recombinant (His)

TMPK-00693

Species: Human

Expression System: E. coli

Frataxin Protein, Cynomolgus, Recombinant (His)

TMPH-02428

Species: Cynomolgus

Expression System: E. coli

Humanin Protein, Human, Recombinant (hFc)

TMPH-01503

Species: Human

Expression System: HEK293

HSF1 Protein, Human, Recombinant (His)

TMPY-02072

Species: Human

Expression System: E. coli

AOC3 Protein, Human, Recombinant (His)

TMPJ-00380

Species: Human

Expression System: Human Cells

WalK Protein, S. aureus, Recombinant (His & Myc)

TMPH-03571

Species: Staphylococcus aureus

Expression System: E. coli

ATF-4 Protein, Rat, Recombinant (His & Myc)

TMPH-03274

Species: Rat

Expression System: E. coli

TXNIP Protein, Mouse, Recombinant (His)

TMPH-02929

Species: Mouse

Expression System: Yeast

TXNIP Protein, Human, Recombinant (B2M & His)

TMPH-02200

Species: Human

Expression System: in vitro E. coli expression system

Protein Kinase D2/PRKD2 Protein, Human, Recombinant (His & GST)

TMPY-04406

Species: Human

Expression System: Baculovirus-Insect Cells

Frataxin/FXN Protein, Human, Recombinant (His & Myc)

TMPH-01356

Species: Human

Expression System: E. coli

Caspase-3 Protein, Human, Recombinant (His)

TMPH-01056

Species: Human

Expression System: E. coli

--------- More ---------

カタログ番号	製品名
L2910	Antioxidant Compound Library	1314 compounds
	Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species (ROS) and a biological system's ability to readily detoxify the reactive intermediates or repair the resulting damage. ...
L5300	Mitochondria-Targeted Compound Library	812 compounds
	A unique collection of 812 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine;
L9840	Anti-Alzheimer's Disease Compound Library	986 compounds
	A unique collection of 986 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.

ライブラリー

Antioxidant Compound Library

L2910

Compounds: 1314

Mitochondria-Targeted Compound Library

L5300

Compounds: 812

Anti-Alzheimer's Disease Compound Library

L9840

Compounds: 986